Associate Scientist - Dermatology > Mountain View CA

JOB Description

Turn Biotechnologies is currently seeking a qualified, highly motivated individual for the position of Associate Scientist.

The employee will be a highly motivated and innovative individual responsible for the scientific/technical aspects of evaluating novel mRNA-based therapeutics for the treatment of age-related skin indications using in vitro and ex vivo model systems. This lab-based position will be critical to the development and evaluation of Turn’s cutting-edge technology for its dermatology pipeline.

COMPANY

Based in Mountain View, California, Turn Biotechnologies, Inc. is a development-stage company focused on restoring cells’ youthful vigor to repair damage caused by the aging process. Using a proprietary ERA™ Platform, we develop mRNA medicines that are specially formulated to instruct specific cells in the body to fight disease or repair damaged tissue. We do this by reprogramming the epigenome to restore cell function that people often lose as they age. This approach can be used to revitalize different cells throughout the body. We are researching its applicability across multiple therapeutic areas, including dermatology, ophthalmology, osteocartilage, and skeletal muscular indications.

Responsibilities:

Essential duties of the position include:

  • Development and application of dermatologic in vitro and ex vivo model systems that include the use of human skin explants

  • Evaluation of drug delivery, transfection efficiency, and therapeutic efficacy in dermatologic in vitro and ex vivo models using various imaging platforms and analytical methods

  • Processing and analysis of human and animal tissues

  • Establishment and maintenance of cell and tissue culture model systems

  • Performance of cell-based assays and analytical techniques including qPCR, ELISA, western blotting, imaging, immunocytochemistry, immunofluorescence microscopy, flow cytometry, FACS, etc.

  • Organize data, maintain detailed records, and effectively communicate results

  • Develop, validate, and write laboratory protocols and technical reports

Additional duties may include:

  • Specialized functional cell assays specific to designated indication areas

  • Development of specialized functional cell and tissue assays in wound healing, angiogenesis, extracellular matrix, and stem cell niche compartments 

  • Live animal imaging and simple biodistribution and safety measurements

  • Specialized tissue functional assays specific to listed indication areas

Qualifications

Education/Experience:

  • PhD in cellular biology, biochemistry, molecular biology, or related discipline

  • 5-7 years’ experience (beyond Ph.D., including post-doctoral work) in dermatology-related translational research

  • Industry experience is a significant plus

  • Experience in cell and tissue culture work and in vitro assays

  • Experience in small (rodent) animal handling and tissue evaluation

  • Collaboration with other team members and across company programs

  • Excellent verbal and written communication skills

Auxiliary:

  • In addition to dermatology, experience in one or more of the focal application areas: Immunology, skeletal muscular and oncology will be a plus, but not essential

  • Background in gene therapeutics testing 

  • Novel animal model system application and adaptation

REQUIRED Characteristics

  • Ownership mindset

  • Ability to achieve goals and milestones with quality, precision, and speed

  • Problem solving and troubleshooting capabilities

  • Strong work ethic

  • Proactive and organized

  • Quick learner

WHY TURN?

  • We are a close-knit, collaborative team, passionate about anti-aging and longevity to improve age-related disease and the quality of people’s lives

  • You will be a vital part of the company and have tremendous impact on its success

  • Competitive compensation & benefits package (medical, dental, vision, life insurance)

  • 401K, FSA, and flexible PTO

  • Employee Assistance Program

Turn Biotechnologies is an equal opportunity employer and values diversity. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status or disability status.