Scientist – Synthetic Chemistry CMC > Mountain View CA

JOB Description

Turn Biotechnologies is seeking an excellent synthetic chemist at PhD level in our CMC group. This is a full-time position based in our labs in Mountain View, CA.

COMPANY

Based in Mountain View, California, Turn Biotechnologies, Inc. is a development-stage company focused on restoring cells’ youthful vigor to repair damage caused by the aging process. Using a proprietary ERA™ Platform, we develop mRNA medicines that are specially formulated to instruct specific cells in the body to fight disease or repair damaged tissue. We do this by reprogramming the epigenome to restore cell function that people often lose as they age. This approach can be used to revitalize different cells throughout the body. We are researching its applicability across multiple therapeutic areas, including dermatologic conditions, pulmonary disease, osteoarthritis and ophthalmology.

Responsibilities:

Essential duties of the position include:

  • Conducting multi-step synthesis and optimization through effective reaction planning, troubleshooting and systematic analysis

  • Purifying and characterizing compounds using a variety of techniques, including column chromatography, crystallization, LCMS, NMR, HPLC, etc.

  • Interpreting SAR data and designing novel organic compounds with improved properties of interest

  • Enabling chemistry via new technologies

  • Collaborating with multidisciplinary teams of scientists to achieve milestones and win together

  • Maintaining all appropriate corporate standards for lab safety and hazardous material management

  • Maintaining a lab notebook, instrument and inventory records in accord with department guidance and regulatory requirements

  • Drafting reports and preparing and presenting summaries of work for the department and projects. Writing regulatory submissions

  • Functioning as a company representative to Contract Research/Manufacturing Organizations

Qualifications

  • PhD in organic synthesis

  • 3-4 years of industrial experience in organic synthesis, medicinal chemistry, chemical development or related field

  • Prior experience with lipid synthesis and polymer chemistry is preferred.

  • Record of excellence in chemistry research with innovative contributions.

  • Strong and independent problem-solving and troubleshooting abilities.

  • Experience in the preparation of regulatory submissions.

  • Experience with outsourcing work to CMOs or CROs, tech transfer, and the ability to supervise projects.

DESIRABLE Characteristics

  • A good team player who is able to work well within and across teams to achieve goals

  • Proficient in presenting data and results in group settings

  • Flexible and can prioritize/accommodate demanding work schedules as required

  • Experienced writing scientific reports

  • Excellent oral and written communication skills

  • Ability to work independently and in a team environment

  • Emotionally intelligent; a “whatever it takes” attitude

Turn Biotechnologies is an equal opportunity employer and values diversity. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.